Cambridge Healthtech Institute’s 4th Annual

Cell Line Development

Technologies and Best Practices for Engineering Robust Cell Lines

23-24 March 2022

As the biopharma field becomes increasingly more complex, the engineering of cell lines remains a foundation step for developing biologic drugs. This foundation applies emerging research and breakthrough strategies to achieve cell lines that accomplish project goals quickly and inexpensively. In support of these goals, the 4th Annual Cell Line Development conference offers an expert faculty sharing strategies and best practices on codon optimization, vector construction, and engineering of clones and host systems. Presentations for 2022 reflect a focus on emerging modalities, new technologies, quality systems and next-generation informatics.

Coverage will include, but is not limited to:

CHO-Based Cell Lines
• Characterisation and control of instabilities
• Engineering strategies
• Optimizing culture performance

Problems and Solutions 
• Chain mispairing for bi- and multi-specific antibodies
• Optimizing media development
• Understanding and controlling glycosylation

Optimizing Cell Line Development
• Improving cell line robustness and titer
• Using QbD approaches to improve cell culture process control
• Workflows and technologies to improve speed and efficiency

Cell Selection and Clone Development
• Early selection methods
• Predictive modeling 
• Systems and synthetic biology technologies

Cell and Gene Therapies
• Clone selection for AAV-based gene therapies
• Isolation and growth of novel cell lines
• Overcoming the challenges of lentiviral vector cell therapies

Emerging Technologies
• Cell imaging
• Novel alternative expression systems
• NGS, ‘omics technologies, machine learning 

If you would like to submit a proposal to give a presentation at this meeting, please click here.

The deadline for priority consideration is Friday 10 September.

All proposals are subject to review by session chairpersons and/or the Scientific Advisory Committee to ensure the overall quality of the conference program. Additionally, as per Cambridge Healthtech Institute’s policy, a select number of vendors and consultants who provide products and services will be offered opportunities for podium presentation slots based on a variety of Corporate Sponsorships.


For more details on the conference, please contact:

Kent Simmons

Senior Conference Director

Phone: 1-207-329-2964



For partnering and sponsorship information, please contact:


Companies A-K

Sherry Johnson

Business Development Manager

Cambridge Healthtech Institute

Phone: 781-972-1359



Companies L-Z

Jon Stroup

Senior Business Development Manager

Cambridge Healthtech Institute

Phone: 781-972-5483


Speaker Proposal