Cambridge Healthtech Institute’s 6th Annual

Cell Line Development

New Technologies, Big Data Solutions, and Best Practices for Engineering Robust Cell Lines

20-21 March 2024


As the biopharma field becomes increasingly more complex, the engineering of cell lines remains a foundation step for developing biologic drugs. This foundation applies emerging research and breakthrough strategies to achieve cell lines that accomplish project goals quickly and inexpensively. In support of these goals, the 6th Annual Cell Line Development conference offers an expert faculty sharing strategies and best practices on cell engineering, engineering for emerging modalities, new technologies, and the integration of modeling and machine learning into this stage of upstream processing.


Coverage will include, but is not limited to:


Cell Engineering

  • Engineering intracellular transport
  • Genome-scale modeling to guide cell line performance improvement
  • Next-generation technologies for cell line engineering and gene editing; resolving IP constraints


Cell Line Development for Novel Modalities

  • Cytokine fusions
  • Engineering producer cell lines for viral vectors
  • Synthetic biology to engineer cell and gene therapy payloads


Emerging Technologies

  • Novel alternate expression systems
  • Strategies and technologies to expand the use of non-clonal pools
  • Transcriptomic analysis to characterise cell behavior


Modeling and Machine Learning in Cell Line Development

  • Machine learning for early identification of promising clones
  • Modeling metabolic pathways
  • Systems biology models for CLD in complex multispecific formats


Problems and Solutions

  • Considerations and strategies for moving to alternative cell lines
  • Modulating glycosylation
  • Resolving chromosomal instability


The deadline for priority consideration is Friday 22 September.


All proposals are subject to review by session chairpersons and/or the Scientific Advisory Committee to ensure the overall quality of the conference program. Additionally, as per Cambridge Healthtech Institute’s policy, a select number of vendors and consultants who provide products and services will be offered opportunities for podium presentation slots based on a variety of Corporate Sponsorships.


Opportunities for Participation:



For more details on the conference, please contact:

Kent Simmons

Senior Conference Director

Cambridge Healthtech Institute

Phone: (1+) 207-329-2964



For sponsorship information, please contact:


Companies A-K

Phillip Zakim-Yacouby

Senior Business Development Manager

Cambridge Healthtech Institute

Phone: (1+) 781-247-1815



Companies L-Z

Aimee Croke

Business Development Manager

Cambridge Healthtech Institute

Phone: (1+) 781-292-0777