2023 POSTER PRESENTATIONS

Poster Award Winners will be announced Wednesday and Thursday at 10:45.

POSTER SESSION A  (Tuesday-Wednesday morning)

A01: Strategies to Increase Recovery of Low Isoelectric Products During Chromatographic Clarification of mAb CHO Cell Cultures, Presented by Hani E., 3M

A02: CASPON Technology - A Platform Process for Non-Platform Proteins Using Escherichia coli, Presented by Christoph K., ACIB GmbH

A03: Osmolality as a Key Metric Within Cryopreservation, Presented by Kendal S., Advanced Instruments

A04: Improving MAbs Purification in Downstream Processes, Presented by Yaiza L., Agarose Bead Technologies

A05: Enabling Bioprocessing of Next-Generation Therapeutics with Optimer Affinity Ligands, Presented by Ilknur D., Aptamer Group

A06: (Un)Fit for Function: Solving Upstream Variability with Polymer Chemistry, Presented by Philipp H., BASF SE

A07: Purifying Challenging Entities: Capture of Bispecific Antibodies and Removal of Product-Related Impurities, Presented by Henry C., Cytiva

A08: Mechanistic Modeling Workflow for Chromatography Simplified with Precharacterized f(x) Columns, Presented by Katrin S., Cytiva

A09: A Streamlined Data Analysis Workflow for Enhanced New Peak Detection (NPD) in the Multi-Attribute Method (MAM), Presented by Dominik M., Genedata AG

A10: Expediting Lentiviral Vector Production with Automated Bioreactors and Design of Experiments, Presented by Jens M., Sartorius Stedim Cellca GmbH

A11: Activity Based Protein Profiling (ABPP): Detection of HCPs Degrading the Polysorbate, Presented by Yu-Hsien L., Novartis Pharma AG

A12: Optimization of Media Composition by Flux Balance Analysis, Presented by Katrin P., Novartis Pharma Austria GmbH

A13: Empty and Full Separation of Adeno-Associated Virus Vectors by Anion Exchange Membrane Chromatography, Presented by Salete F., Pall Life Sciences

A14: Scalable Ultrafiltration-Diafiltration (UF/DF) Process of Clarified Plasmid DNA (pDNA) Using T-Series Cassettes with Omega™ Membrane, Presented by Claudia G., Pall Life Sciences

A15: Development of a Novel Helper Plasmid: One Step Closer to the Next Generation rAAV Vectors, Presented by Laure R., Polyplus

A16: Accurate Peptide Mapping of Biotherapeutic Proteins Using Novel Improved Recombinant Trypsin and Arginine-Specific Protease, Presented by Sergei S., Promega Corporation

A17: Praesto Jetted A50 HipH: A Novel Protein A Resin Designed Specifically for Elution of Fc-Containing Molecules at Higher pH Levels, Presented by Mark H., Purolite

A18: Off-Gas Based Soft-Sensor for Real-Time Monitoring of Biomass and Metabolism in Chinese Hamster Ovary Cell Continuous Fermentation Processes in Single-Use Bioreactors, Presented by Tobias W., Roche Diagnostics GmbH

A19: Quantitative Structural Activity Relationship Modelling (QSAR) of Effects of Biological Additive Composition in Cell Culture Growth Media on Cell Culture Performance and mAb Production, Presented by Ronan O., ROK Bioconsulting

A20: Applicability of Centrifugal Partition Chromatography in Downstream Bioprocessing, Presented by Zalan K., RotaChrom Technologies LLC

A21: Biophysical Characterization of Adeno-Associated Virus Vectors Using Ion-Exchange Chromatography Coupled to Light Scattering Detectors, Presented by Christina W., Takeda

A22: The Use of Raman Spectroscopy as a Process Analytical Technology (PAT) tool for Biopharmaceutical Process Monitoring, Presented by Lin C., Thermo Fisher Scientific

A23: Analysis of Host Cell Proteins in Protein A Eluates of mAb-Based Therapeutic Proteins, Presented by Sherin P., University of Applied Sciences and Arts Northwestern Switzerland

A24: Online Optimization Approach Using Model Predictive Control for Resin Aging in Capture Chromatography, Presented by Touraj E., University of Natural Resources and Life Sciences

A25: Multicomponent Adsorbtion as a Hindrance of Fab Fragment Purification, Presented by Alexander J., University of Natural Resources and Life Sciences

A26: Genomic dsDNA Related Membrane Fouling During Sterile Filtration of Cell Lysates, Presented by Markus B., University of Natural Resources and Life Sciences

A27: Protein Quaternary Structures in Solution Are a Mixture of Multiple Oligomeric Forms, Presented by Shir M., Weizmann Institute of Science

A28: Increased Productivity with Rapid CIP Using GORE Protein Capture Devices with Protein A and Demonstrated Scalability, Presented by Jeff C., WL Gore and Associates, Inc.

POSTER SESSION B  (Wednesday afternoon-Thursday)

B01: Mixed-Mode Chromatography for rAAV8 Scalable Purification, Presented by Jean-Francois D., Bio-Rad Laboratories

B02: High Throughput Screening for Product Quality Attributes Early During Mammalian Cell Line Generation, Presented by Katharina K., Boehringer Ingelheim Pharma GmbH & Co. KG

B03: Adeno-Associated Virus Production Platform Performance for 2L and 50L Scales, Presented by Amna A., Cell & Gene Therapy Catapult

B04: Development of an End-to-End Closed iPSC Expansion Process Using a Cell Specific Perfusion Regime for Process Intensification, Presented by Patrick S., Cell & Gene Therapy Catapult

B05: New Cell Engineering Method for Increasing Recombinant Therapeutic Antibody Productivity Up To 10-Fold in Batch CHO Cultures, Presented by Larry F., CHO Plus

B06: Optimizing Screens in the Cell Line Development Workflow, Presented by Seungjo P., Cytiva

B07: Clarification with Seitz™ Filters for Adherent and Suspension Adeno-Associated Virus (AAV) Cultures, Presented by Xenia M., Pall Life Sciences

B08: Efficient and Reliable GCT Solutions from Research to Clinical, Presented by Daksha P., GenScript USA, Inc.

B09: Aura+: High Throughput, Low Volume Product Stability and Purity Analysis for Gene and Cell Therapies, Presented by Paul D., Halo Labs

B10: Process Analytical Technology (PAT) for Automated, Real-Time Control of Continuous Manufacturing of Monoclonal Antibodies (mAbs), Presented by Shantanu B., Indian Institute of Technology Delhi

B11: Expediting Cell Line Development by Defining Ubiquitous Chromatin Opening Elements (UCOE®) Molecular Mechanisms of Action, Presented by Saba H., King's College London

B12: Inducible Cas9 Expressing T Cells: An Innovative Platform for T Cell Engineering, Presented by Ariel G., Lonza Biologics

B13: Challenges with Scaling-Up High Inoculum Density Production with Raman Feedback Control, Presented by Anthony B., Lonza Biologics

B14: Predictive Modeling of Concentration-Dependent Viscosity Behavior of Monoclonal Antibody Solutions Using Artificial Neural Networks, Presented by Daniel K., Lonza Biologics

B15: Automation for Reduced Timelines and Improved Clonality Assurance in CHO Cell Line Development, Presented by Harrison G., Menarini Biotech UK

B16: Benefit-Risk Assessment of Advanced Continuous Manufacturing Technologies, Presented by Ljubomir G., Merck Chemicals GmbH

B17: Single-Cell Printing, and Screening of Cell Lines for Monoclonality Verification Using an Impedance-Based Single-Cell Dispenser and High-Throughput Fluorescence-Based Imager, Presented by Janet G., Molecular Devices UK Ltd.

B18: Bridging Immunodetection to Identification for Host Cell Protein Analysis, Presented by Nicolas L., Novartis Pharma AG

B19: Good Manufacturing Practice (GMP) Adeno-Associated Virus (AAV) Manufacturing Process Using Transient Transfection in a 2000 L Bioreactor (Theoretical Approach), Presented by Roberto C., Pall Life Sciences

B20: Scientific Solutions for Regulatory Guidelines: Unlocking AAV Product Testing, Presented by Diogo A., Sartorius Stedim Cellca GmbH

B21: The 4Cell® CHO CLD Platform: Identifying High Producers Through Improved Clone Selection Using Sartorius´ CellCelector™ Single Cell Cloning Technology and an automated 96well Small-Scale Fed-Batch, Presented by Juliana B., Sartorius Stedim Cellca GmbH

B22: Rapid On-Line Analysis of Limiting Amino Acids Using the Autosampling System Numera® and the Software Lucullus®, Presented by Mohi A., Securecell BV

B23: The Power of On-Line Analytics for Event-Based Bioprocess Control with Lucullus®, Presented by Pascal V., Securecell BV

B24: A New Method to Improve Cryopreservation of Stem Cells with Low DMSO Concentration: An Experimental Study on the Influence of Freezing Geometry, Presented by Rafaela N., SmartFreez

B25: A New Scale-Down Strategy for Assessment of mAbs’ Manufacturing Freeze-Thaw Stability, Presented by Andreia D., SmartFreez

B26: Adaption of a CHO DP-12 Cell Line and Identification of Host Cell Proteins Using LC QTOF Mass Spectrometry, Presented by Jodie M., University of Limerick

B27: Extracellular Peptide Production in Escherichia coli, Presented by Martin G., University of Natural Resources and Life Sciences

B28: Rapid and High Throughput IgG Quantification in Crude Cell Culture Samples Using Multiwell Plates, Presented by Eligio I., ValitaCell, part of Beckman Coulter Life Sciences

ADDITIONAL VIRTUAL POSTERS ~ Online Only

V01: Downstream Process Technologies at Menarini Biotech, Presented by Desiree E., Menarini Biotech UK

V02: Strategies to Remove Single Cell Cloning from Genetic Knock Out Screens in Host Cell Line Engineering, Presented by Ann-Cathrin L., Sartorius Stedim Cellca GmbH