Cambridge Healthtech Institute’s 4th Annual

Downstream Processing and Continuous Manufacturing

Reducing Costs by Optimizing Recovery, Purification and Continuous Processing

16-17 March 2021

 

Cambridge Healthtech Institute’s Downstream Processing and Continuous Manufacturing conference discusses the latest developments in the capture, recovery and purification of biotherapeutics in continuous and non-continuous settings with data driven case studies on next-generation DSP technologies and strategies across a range of modalities. Topics will latest updates on continuous chromatography, recovery and purification, automation and digitalization, process control, chromatography and HTPD.

 

Coverage will include, but is not limited to:

 

Downstream Processing

 

  • Next-gen DSP strategies
  • Emerging DSP technologies
  • New modalities – antibody variants, nanobodies, bispecifics, gene therapies, viral vectors, antibody fragments, fusion proteins
  • HTPD and modelling for to improve process development, mechanistic modelling
  • Optimizing resin performance, new Protein A, regeneration strategy, chemical resin
  • Reducing impurities
  • Optimizing existing downstream processes
  • Digitalization and AI to improve processes and workflows
  • Automation, HTPD, modelling and process characterization
  • Reducing impurities and contaminants
  • HCP and viral safety

 

Continuous Processing

 

  • Continuous process development – from perfusion to purification
  • Optimizing perfusion – modelling comparisons against fed-batch
  • Ensuring process stability
  • Harvest step
  • Implementing perfusion into downstream operations
  • Continuous chromatography
  • Process control, robustness and monitoring
  • Online analysis – PAT, online HPLC, multivariate analysis
  • Viral safety in a continuous process
  • Preparing for commercialization
  • Facility design for continuous processing and process intensification
  • Digitalization
  • Semi-continuous
  • Defining a batch, process validation
  • Comparability strategies following process changes

 

If you would like to submit a proposal to give a presentation at this meeting, please click here.

 

The deadline for priority consideration is Friday 30 October.

 

All proposals are subject to review by session chairpersons and/or the Scientific Advisory Committee to ensure the overall quality of the conference program. Additionally, as per Cambridge Healthtech Institute’s policy, a select number of vendors and consultants who provide products and services will be offered opportunities for podium presentation slots based on a variety of Corporate Sponsorships.

 

For more details on the conference, please contact:

Daniel Barry

Senior Conference Director

Cambridge Healthtech Institute

Phone: 07837 651 303

Email: dbarry@healthtech.com

 

For partnering and sponsorship information, please contact:

 

Companies A-K

Sherry Johnson

Business Development Manager

Cambridge Healthtech Institute

Phone: 781-972-1359

Email: sjohnson@cambridgeinnovationinstitute.com

 

Companies L-Z

Jon Stroup

Senior Business Development Manager

Cambridge Healthtech Institute

Phone: 781-972-5483

Email: jstroup@healthtech.com