Cambridge Healthtech Institute Training Seminars offer real-life case studies, problems encountered and solutions applied, and extensive coverage of the basic science underlying each topic. Experienced Training Seminar instructors offer a mix of formal
lectures, interactive discussions and activities to help attendees maximize their learning experiences. These immersive trainings will be of value to scientists from industry and academic research groups who are entering new fields – and to
those working in supporting roles that will benefit from an in-depth briefing on a specific aspect of the industry.
Tues 24- Wed 25 March 2020
Design of Experiments for Bioprocess Analysis - Detailed Agenda
Marcello Fidaleo, PhD, Associate Professor, University of Tuscia; Teaching Fellow, Biomanufacturing Training and Education Center, North Carolina State University
The aim of this training seminar is to provide the attendees with an introduction to the Design of Experiments (DoE) methods applied to analysis and optimization of bioprocesses. It focuses on the application of DoE methods using lectures, JMP statistical
software (SAS Institute, NC), and case studies. The case studies, which provide real data, focus on microbial fermentation, chromatography, and pharmaceutical product formulation. Attendees will receive a practical overview of the following topics:
basic statistical concepts for DoE; how to use factorial, fractional factorial, and response surface designs for the characterization and optimization of bioprocesses; how to interpret the output of experimental design software (normal probability,
interaction and contour plots, or estimated coefficients tables for factorial or surface response models). Attendees are invited to bring their own laptops to get hands-on experience with JMP (it is suggested to preinstall a free 30-day trial downloadable
online at www.jmp.com), pen, and notepaper.
Tues 24- wed 25 March 2020
Intro to Gene Therapy and Viral Vectors - Detailed Agenda
Jerrod Denham, Principal, Dark Horse Consulting
Andrew Steinsapir, Consultant, Dark Horse Consulting
In the age of gene therapy, there is a significant demand for scientists trained in the “dark arts” of viral vector production and analysis. This 1.5-day course has been specifically created for gene therapy scientists looking for a solid
understanding of the analysis, quality control, and manufacture of AAV-, lentiviral- and retroviral-based products.