Cambridge Healthtech Institute ’s 2nd Annual

Continuous Processing for Biopharmaceuticals

19-20 March 2019

 

Continuous processing has proven to reduce manufacturing costs and increase efficiencies, but what are the practical considerations when implementing this technology at scale? Which technology gaps still remain, how can companies ensure process control and stability, and where should companies be focusing resources and investments to ensure clinical and commerical success?

 

Cambridge Healthtech Institute’s Continuous Processing for Biopharmaceuticals conference focuses on the practical challenges of developing, integrating and implementing continuous processing in biopharmaceutical manufacturing. Key topics include continuous process development from perfusion to purification, process control, robustness and monitoring, viral safety, cost analysis, and ramping up for commercialization, all in line with international regulations.

 

Coverage will include, but is not limited to:

 

  • Continuous Process Development – From Perfusion to Purification
  • Optimizing perfusion – modelling comparisons against fed-batch
  • Fed-batch process intensification
  • Ensuring process stability
  • Harvest step
  • Implementing perfusion into downstream operations
  • Continuous chromatography
  • Process Control, Robustness and Monitoring
  • Control strategies – similar to other industries, sensors, control aggregates, hierarchy in process control
  • Online analysis – PAT, online HPLC, multivariate analysis
  • Integrating process control
  • Design space characterization and QbD for continuous processing
  • Defining the strategy for cleaning
  • Defining a batch, process validation
  • Viral safety in a continuous process
  • Preparing for Commercialization
  • Business and market pressures for continuous processing – preparing for commercialization
  • Facility design for continuous processing and process intensification
  • What have we learnt from other industries?
  • Technology gaps
  • Risk Assessment strategies – back up systems, developing parallel systems, what happens if something goes wrong
  • Regulatory Requirements and Lifecycle Management
  • How to use continuous processing in existing facilities
  • Semi-continuous
  • Defining a batch, process validation
  • Comparability strategies following process changes

 

If you would like to submit a proposal to give a presentation at this meeting, please click here.

 

The deadline for priority consideration is Friday, 24 August 2018.

 

All proposals are subject to review by session chairmen and/or the Scientific Advisory Committee to ensure the overall quality of the conference program. Additionally, as per Cambridge Healthtech Institute  policy, a select number of vendors and consultants who provide products and services will be offered opportunities for podium presentation slots based on a variety of Corporate Sponsorships.

 

For more details on the conference, please contact:
Daniel Barry

Senior Conference Director

Cambridge Healthtech Institute

Phone: (+1) 781-247-6266
Email: dbarry@healthtech.com

 

For partnering and sponsorship information, please contact:

Companies A-K

Sherry Johnson

Senior Business Development Manager

Cambridge Healthtech Institute

Phone: (+1) 781-972-1359
Email: sjohnson@healthtech.com

 

Companies L-Z

Carolyn Cooke

Business Development Manager

Cambridge Healthtech Institute

Phone: (+1) 781-972-5412
Email: ccooke@healthtech.com