Cambridge Healthtech Institute ’s 2nd Annual

Optimising Cell Culture Technology

Enhancing Knowledge for Growing Cells

19-20 March 2019


The ubiquitous task of culturing cells is recognised as an established technology; yet, meeting the demands of industry pushes the need to increase titre, and decrease the time and resources necessary to meet project goals. The Optimising Cell Culture Technology conference examines strategies to streamline production while ensuring bottom-line quality. The conference will include a session focused on culturing CHO cells (Chinese Hamster Ovary cells), as well as discussions of breakthrough technologies and analytical approaches that support the tasks at hand and lead to greater productivity. CRISPR, modeling and computational insights will be discussed in the continuing efforts to improve yield.

Preliminary Agenda


Proteomic and Phosphoproteomic Characterisation of Growth of Recombinant Chinese Hamster Ovary Cells

Paula Meleady, PhD, Associate Director, National Institute for Cellular Biotechnology, Dublin City University

A Genetic Engineering Strategy for the Improvement of Chinese Hamster Ovary (CHO) Cell Line Development and Performance

Paul Kelly, PhD, Postdoctoral Research Scientist, Cell Engineering Lab, National Institute for Bioprocessing Research and Training (NIBRT)

Engineering CHO Cell Lines for the Production of Hard-to-Produce Proteins

Bjørn Voldborg, MSc, Director, CHO Cell Line Development, The Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark

Difficult to Express Proteins: Identification of Intracellular Production Bottlenecks in CHO Cells

Kerstin Otte, PhD, Professor, Institut of Applied Biotechnology (IAB), Pharmaceutical Biotechnology (PBT), Biberach University of Applied Sciences


Should the Dynamic Nature of Process Operation be Reflected by the Design Space Representation/Characterization?

Moritz von Stosch, PhD, Senior Manager, Drug Substance, Technical R&D, GSK Vaccines

Monitoring the Metabolic State and Productive Capacity of Cells During a Bioprocess

Michael Butler, PhD, Chief Scientific Officer, Research, National Institute of Bioprocessing Research & Training (NIBRT)


Process Intensification

David Brühlmann, PhD, Manager, Biotech Process Sciences Technology & Innovation, Merck Biopharma

Digital Twins for Process Robustness and Control Strategies

Christoph Herwig, PhD, Professor & Head, Bioprocess Engineering, Institute of Chemical Engineering, Vienna University of Technology

Next Generation Single-Cell Dispensing in Cell Line Development

Thomas Kretschmann, Field Application Specialist, cytena


Hybrid Modeling and Intensified DoE -- A Showcase

Gerald Striedner, PhD, Associate Professor, Institute for Biotechnology, University of Natural Resources and Life Sciences (BOKU)

Model-Assisted Cell Culture Control

Björn Frahm, PhD, Professor, Biotechnology and Bioprocess Engineering, and Vice Dean, Life Science Technologies, Ostwestfalen-Lippe University of Applied Sciences

For more details on the conference, please contact:
Mary Ruberry

Senior Conference Director

Cambridge Healthtech Institute

Phone: (+1) 781-972-5421


For partnering and sponsorship information, please contact:

Companies A-K

Sherry Johnson

Senior Business Development Manager

Cambridge Healthtech Institute

Phone: (+1) 781-972-1359


Companies L-Z

Carolyn Cooke

Business Development Manager

Cambridge Healthtech Institute

Phone: (+1) 781-972-5412